Apejuwe:

DPG(D)

Accelerator Kemikali Name	Diphenyl guanidine
Fọọmu Molecular	C₁₃H₁₃N₃
Ilana Molikula
Òṣuwọn Molikula	211.27
Walẹ	1.13-1.19
CAS RARA.	102-06-7

Ni pato:

Nkan	Lulú	Epo lulú	Granular
Ifarahan	Lulú funfun -	Lulú funfun -	Grẹy{0} granulu funfun
MP akọkọ (Min) Ti o tobi ju tabi dọgba si alefa	145.0	145.0	145.0
Pipadanu lori gbigbe (Max) Kere ju tabi dọgba si%	0.30	0.40	0.30
Ash (Max) Kere ju tabi dọgba si%	0.30	0.40	0.30
Awọn iṣẹku lori sieve 150μm, % Kere ju tabi dọgba si	0.10	0.10	-
Akoonu epo,%	-	0.0-2.0	-
granular opin mm	-	-	1.5

Kekuru bi BPG tabi DPG ni Gẹẹsi, o jẹ ipa pataki allosteric ti haemoglobin.

Asopọmọra ti 2,3-DPG ninu awọn sẹẹli ẹjẹ pupa si deoxyhemoglobin ṣe idaduro isọdi aye ti deoxyhemoglobin, nitorinaa idinku isunmọ ti haemoglobin fun O2 ati igbega iyapa ti O2 ati haemoglobin. Paapa nigbati ẹjẹ ba kọja nipasẹ ara, wiwa 2,3-DPG ninu awọn sẹẹli ẹjẹ pupa le ṣe alekun itusilẹ ti O2 fun awọn iwulo àsopọ. Ni afikun, awọn alaisan ti o ni emphysema obstructive ti o lagbara pẹlu iṣọn-ẹjẹ atẹgun ẹdọforo ati awọn eniyan deede le ṣatunṣe àsopọ nipasẹ yiyipada ifọkansi ti 2,3-DPG ninu awọn ẹjẹ pupa nigba ti o dide lati ipele okun si giga giga tabi giga giga ni igba diẹ. Gba iye ti O2.

Ni iwaju BPG, oxygenation ti haemoglobin le ṣe afihan nipasẹ idogba atẹle:

HbBPG + 4O2 → Hb(O2)4 + BPG (Akiyesi: Eyi jẹ ipadasẹhin iyipada)

Ẹka 2,3-diphosphoglycerate Ipa pataki ti 2,3-diphosphoglycerate (2,3-DPG) ninu awọn ẹjẹ pupa ni lati ṣe atunṣe iṣẹ O2 ti hemoglobin.

Iyatọ laarin glycolysis sẹẹli ẹjẹ pupa ti o dagba ati awọn sẹẹli miiran jẹ iṣelọpọ ti 2,3-DPG. Awọn akoonu ti 2,3-DPG jẹ ti o ga julọ ni agbedemeji glycolysis (ninu ẹjẹ iṣọn-ẹjẹ: akoonu ti 2,3-DPG jẹ awọn akoko 177 ati awọn akoko 239 ti 3-phosphoglycerate). Eyi jẹ nitori wiwa diphosphoglycerate (DPG) mutase ati 2,3-DPG phosphatase ninu awọn sẹẹli ẹjẹ pupa. Awọn aati catalyzed nipasẹ awọn ensaemusi meji wọnyi jẹ aibikita. Labẹ awọn ipo deede, ipa esi odi ti 2,3-diphosphoglycerate lori DPG mutase tobi ju idinamọ ti 3-phosphoglycerate, nitorinaa glukosi ninu awọn sẹẹli ẹjẹ pupa tun jẹ glycolysis akọkọ lati ṣe agbejade lactic acid. Nitori iṣẹ kekere ti 2,3-DPG phosphatase, iṣelọpọ 2,3-DPG tobi ju jijẹ silẹ, ti o mu ki awọn ipele ti o ga julọ ti 2,3-DPG ni awọn ẹjẹ pupa.

Awọn afiwe Gbona: ohun imuyara d (dpg), China, olupese, awọn olupese, factory, owo, osunwon, roba kemikali, roba aropo, roba pese sile

Accelerator D (DPG)